Saturday, December 3, 2011

Introduction on age related eye disease study for macular degeneration

According to the Age Related Eye Disease Study made by the U. S. Federal government's National Eye Institute, the risk of developing advanced age-related macular degeneration (AMD) can be reduced by 25% for people who take high levels of antioxidants and zinc. Though the AREDS formulation can not treat AMD, it can help people at high risk of advanced AMD with their remaining vision.


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So you may wonder to know what and how many antioxidants and zinc should be taken in daily in order to reduce the possibility for advanced AMD. The following will list out the AREDS formula eye vitamins and their daily amounts: The first one is Vitamin C with daily amount of 500 milligrams; Second is Vitamin E with 400 international units; Third is beta-carotene with the amount of 15 milligramsï¼›Fourth is zinc oxide at the quantity of 80 milligrams; and the last is copper as cupric oxide with the amount of 2 milligrams in order to keep copper deficiency anemia away from us, which is caused by taking in high levels of zinc.

Presently, the National Eye Institute is preparing for its Age Related Eye Disease Study 2 (AREDS) and this study is planed to be finished in June, 2013. They have recruited 4000 participants in their study. The main purposes of this study 2 are as following: First, it is said macular degeneration antioxidants, lutein and zeaxanthin, and omega-3 LCPUFAs (DHA and EPA) have some good effects to treat AMD and cataract. And the study will test their treatment ability for AMD and cataract and check if they can slow down the progression of these two eye diseases. The second purpose is to test what it will be if we don't have beta-carotene from the ARED formulation and its influence on AMD development and progression. The third purpose is to prove zinc's effect on treating and reducing the progression of AMD. Nowadays, if we want to prove the photographic AMD scales develops from the Age-related Eye Disease Study, we still need some data supporting, so the last purpose of this study is to offer some data to validate this point.

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